Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413413 | 0.89 | ESR1 (0.40) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10547546 | 0.88 | NR1I2 (0.45) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10414291 | 0.88 | NR1I2 (0.44) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10413863 | 0.87 | NR1I2 (0.46) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10414296 | 0.86 | NR1I2 (0.34) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10413854 | 0.86 | NR1I2 (0.46) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10413866 | 0.86 | NR1I2 (0.46) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10413416 | 0.85 | NR1I2 (0.45) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10550639 | 0.84 | NR1I2 (0.46) | NR1I2PGRPTGS2HTR2CMAPT | |
| SCHEMBL10750415 | 0.84 | NR1I2 (0.51) | NR1I2PGRPTGS2HTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912214-A | Containing azelidin-2-one ring | HOFFMAN-LA ROCHE INC. (US) | 1990-03-27 | — | — | US | disclosed |