Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.65 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | APEX1 | P27695 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415785 | 0.95 | MAPT (0.65) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL10415750 | 0.95 | NR1I2 (0.63) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL10416364 | 0.93 | PTGS1 (0.73) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL10415870 | 0.93 | NR1I2 (0.60) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL10415820 | 0.93 | NR1I2 (0.59) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL9876986 | 0.92 | NR1I2 (0.58) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL9876590 | 0.92 | NR1I2 (0.58) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL10415793 | 0.91 | PTGS1 (0.58) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| SCHEMBL10415519 | 0.91 | PTGS1 (0.58) | MAPTNR1I2PPARGSLC22A6SLC22A8 | |
| Cefuzonam SCHEMBL9573537 | 0.90 | NR1I2 (0.73) | MAPTNR1I2PPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902710-A | THIO-, SULFINYL-, OR SULFONYL-PROPANAMINES; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS; NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0157000-A2 | Ester of cephalosporin derivatives | AMERICAN CYANAMID COMPANY (US) | 1985-10-09 | — | — | EP | disclosed |