Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924937 | 1.00 | NPSR1 (0.53) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL10414398 | 1.00 | NPSR1 (0.53) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL8579928 | 0.88 | NPSR1 (0.63) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL348236 | 0.88 | NPSR1 (0.63) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL4576754 | 0.88 | NPSR1 (0.63) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL10414396 | 0.84 | NPSR1 (0.48) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL10414395 | 0.84 | NPSR1 (0.48) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL20924935 | 0.81 | NPSR1 (0.54) | NPSR1ALOX15HCAR2MGAMGAA | |
| SCHEMBL9461967 | 0.81 | HCAR2 (0.43) | HCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9461969 | 0.81 | HCAR2 (0.43) | HCAR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973695-A | FROM UNSATURATED ALDEHYDE OR KETONE WITH OXODIESTER | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |