Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088353 | 0.89 | KCNH2 (0.74) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL10586588 | 0.84 | KCNH2 (0.81) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL10586593 | 0.84 | KCNH2 (0.81) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8554870 | 0.84 | HSD17B10 (0.68) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL9085249 | 0.83 | KCNH2 (0.58) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL9086828 | 0.82 | KCNH2 (0.54) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8111805 | 0.82 | KCNH2 (0.54) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10879015 | 0.81 | KDM4E (0.70) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL8623001 | 0.80 | KCNH2 (0.54) | KCNH2HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL9088309 | 0.80 | KCNH2 (0.71) | KCNH2HRH3HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |