Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831471 | 0.89 | TSHR (0.55) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL10658779 | 0.88 | TSHR (0.48) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL10416987 | 0.87 | TSHR (0.47) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8358753 | 0.85 | TSHR (0.46) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9831772 | 0.83 | TSHR (0.52) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8356670 | 0.83 | TSHR (0.43) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9831797 | 0.79 | KMT2A (0.47) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9832899 | 0.79 | KMT2A (0.49) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8372378 | 0.78 | KMT2A (0.44) | TSHRKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL10667683 | 0.77 | TSHR (0.50) | TSHRALDH1A1USP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954163-A | PRE-AND POSTEMERGENCE HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| US-4886883-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| US-4818273-A | Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides | THE DOW CHEMICAL COMPANY (US) | 1989-04-04 | — | — | US | disclosed |