Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911778 | 0.86 | CXCR4 (0.43) | CXCR4EPHX2KDM4ELMNACXCL12 | |
| SCHEMBL56457 | 0.82 | KDM4E (0.42) | CXCR4EPHX2KDM4ELMNACXCL12 | |
| SCHEMBL32678344 | 0.81 | CXCR4 (0.41) | CXCR4EPHX2KDM4ELMNACXCL12 | |
| SCHEMBL773610 | 0.81 | CXCR4 (0.41) | CXCR4EPHX2KDM4ELMNACXCL12 | |
| SCHEMBL4522392 | 0.80 | CXCR4 (0.46) | CXCR4KDM4ECXCL12HRH4HRH3 | |
| SCHEMBL18692027 | 0.80 | CXCR4 (0.46) | CXCR4KDM4ECXCL12HRH4HRH3 | |
| SCHEMBL14015575 | 0.80 | CXCR4 (0.41) | CXCR4EPHX2KDM4ELMNACXCL12 | |
| SCHEMBL4530519 | 0.80 | CXCR4 (0.49) | CXCR4KDM4ELMNACXCL12HRH4 | |
| SCHEMBL10417498 | 0.79 | CXCR4 (0.43) | CXCR4EPHX2KDM4ELMNACXCL12 | |
| SCHEMBL15360533 | 0.77 | CXCR4 (0.42) | CXCR4EPHX2KDM4ECXCL12HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968760-A | SILICON-CARBON BONDED RADICALS WITH BASIC NITROGEN | WACKER-CHEMIE GMBH (DE) | 1990-11-06 | — | — | US | disclosed |