Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN12 | Q05209 | 1/20 | 0.73 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.73 |
| ▸ | MYC | P01106 | 3/20 | 0.71 |
| ▸ | MAX | P61244 | 3/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.67 |
| ▸ | MMP3 | P08254 | 2/20 | 0.67 |
| ▸ | MMP13 | P45452 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417661 | 1.00 | PTPN12 (0.73) | PTPN12PTPN22MYCMAXAKR1B1 | |
| SCHEMBL6887171 | 0.90 | PTPN12 (0.70) | PTPN12PTPN22MYCMAXAKR1B1 | |
| SCHEMBL6887175 | 0.90 | PTPN12 (0.70) | PTPN12PTPN22MYCMAXAKR1B1 | |
| SCHEMBL12008740 | 0.88 | MYC (0.83) | PTPN12PTPN22MYCMAXAKR1B1 | |
| SCHEMBL6879204 | 0.87 | AKR1B1 (0.70) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL6879207 | 0.87 | AKR1B1 (0.70) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL6886567 | 0.87 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL10491513 | 0.87 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL6886565 | 0.87 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL12661909 | 0.86 | PTPN12 (0.75) | PTPN12PTPN22AKR1B1PTPN1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965155-A | HIGH MOLECULAR WEIGHT POLYMERCONTAINING RHODANINE DERIVATIVE | MITA INDUSTRIAL CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |