Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.78 |
| ▸ | HTR2C | P28335 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | PPARG | P37231 | 2/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.75 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.75 |
| ▸ | ALB | P02768 | 1/20 | 0.75 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.66 |
| ▸ | APEX1 | P27695 | 3/20 | 0.66 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10418637 | 1.00 | NR1I2 (0.78) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10535346 | 1.00 | NR1I2 (0.78) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11217052 | 0.99 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Hydrochloric Acid SCHEMBL10417892 | 0.99 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Hydrochloric Acid SCHEMBL10417890 | 0.99 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11151304 | 0.92 | TDP1 (0.75) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11151291 | 0.92 | TDP1 (0.75) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10418935 | 0.92 | TDP1 (0.69) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10418936 | 0.92 | TDP1 (0.69) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Water SCHEMBL11141115 | 0.91 | TDP1 (0.74) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4380541-A | 2-AMINO THIAZOL-4-YL- | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-19 | — | — | US | claimed |
| US-4923998-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4841062-A | CHEMICAL INTERMEDIATES | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4822888-A | INTERMEDIATES FOR CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4604456-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1986-08-05 | — | — | US | disclosed |
| US-4563522-A | BACTERICIDAL ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| US-4460583-A | ANTIBIOTIC, BACTERICIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4447430-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4427674-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4425341-A | CEPHALOSPORING | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4400379-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-08-23 | — | — | US | disclosed |
| US-4399133-A | ADMINISTERING, INFECTIONS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-08-16 | — | — | US | disclosed |
| US-4393059-A | BACTERICIDAL CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4294960-A | 7-[2-(2-Aminothiazol-4-yl)-2-cyclopentyloxyiminoacetamido]-3-cephem-4-carboxylic acid (synisomer) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-10-13 | — | — | US | disclosed |