Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 16/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10418884 | 1.00 | TLR4 (0.51) | TLR4SELP | |
| SCHEMBL8431958 | 0.93 | TLR4 (0.54) | TLR4SELP | |
| SCHEMBL8436288 | 0.93 | TLR4 (0.54) | TLR4SELP | |
| SCHEMBL6800991 | 0.93 | TLR4 (0.57) | TLR4SELP | |
| SCHEMBL6795483 | 0.93 | TLR4 (0.57) | TLR4SELP | |
| SCHEMBL6807623 | 0.93 | TLR4 (0.57) | TLR4SELP | |
| SCHEMBL6807622 | 0.93 | TLR4 (0.57) | TLR4SELP | |
| SCHEMBL10418883 | 0.93 | TLR4 (0.54) | TLR4SELP | |
| SCHEMBL8431429 | 0.93 | TLR4 (0.53) | TLR4SELP | |
| SCHEMBL10613216 | 0.91 | TLR4 (0.60) | TLR4SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |