Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419683 | 1.00 | CYP1A2 (0.32) | CYP1A2CYP2D6CYP2C19CA12CA1 | |
| SCHEMBL10418109 | 0.87 | MEN1 (0.37) | CYP1A2CYP2C19MAPT | |
| SCHEMBL10418108 | 0.87 | MEN1 (0.37) | CYP1A2CYP2C19MAPT | |
| SCHEMBL10418758 | 0.77 | MAPT (0.32) | MAPTL3MBTL1 | |
| SCHEMBL10418756 | 0.77 | MAPT (0.32) | MAPTL3MBTL1 | |
| SCHEMBL10418165 | 0.75 | MEN1 (0.42) | CYP1A2CYP2C19MAPT | |
| SCHEMBL10418164 | 0.75 | MEN1 (0.42) | CYP1A2CYP2C19MAPT | |
| SCHEMBL10419252 | 0.72 | MEN1 (0.40) | CYP1A2CYP2C19MAPTL3MBTL1 | |
| SCHEMBL10419253 | 0.72 | MEN1 (0.40) | CYP1A2CYP2C19MAPTL3MBTL1 | |
| SCHEMBL10418126 | 0.71 | MEN1 (0.40) | CYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971979-A | Antiinflammatory agents | RHONE-POULENC SANTE (FR) | 1990-11-20 | — | — | US | disclosed |
| US-4886835-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC SANTE (FR) | 1989-12-12 | — | — | US | disclosed |