Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10491537 | 0.91 | HTT (0.47) | FOLH1HTTMAPTRXFP1HDAC3 | |
| SCHEMBL1491987 | 0.86 | EPOR (0.51) | FOLH1TPSAB1TPSD1TPSG1EPOR | |
| SCHEMBL22804052 | 0.86 | EPOR (0.51) | FOLH1TPSAB1TPSD1TPSG1EPOR | |
| SCHEMBL3776750 | 0.86 | EPOR (0.51) | FOLH1TPSAB1TPSD1TPSG1EPOR | |
| SCHEMBL4852056 | 0.85 | EPOR (0.46) | FOLH1TPSAB1TPSD1TPSG1MAPK1 | |
| SCHEMBL9574165 | 0.85 | EPOR (0.46) | FOLH1TPSAB1TPSD1TPSG1MAPK1 | |
| SCHEMBL10477497 | 0.85 | EPOR (0.46) | FOLH1TPSAB1TPSD1TPSG1MAPK1 | |
| SCHEMBL4837028 | 0.83 | FOLH1 (0.50) | FOLH1HTTMAPTRXFP1SMN1; SMN2 | |
| SCHEMBL3648287 | 0.83 | FOLH1 (0.52) | FOLH1HTTALDH1A1 | |
| SCHEMBL3222447 | 0.82 | EPOR (0.52) | FOLH1TPSAB1TPSD1TPSG1EPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916119-A | IMMUNOSTIMULANT TRIPEPTIDES | RHONE-POULENC INDUSTRIES (FR) | 1990-04-10 | — | — | US | disclosed |
| US-4868326-A | Process for the preparation of N6 -benzyloxycarbonyl-2,6-diaminopimelamic acid in the L,L or D,D or racemic forms | RHONE-POULENC SANTE (FR) | 1989-09-19 | — | — | US | disclosed |
| US-4742048-A | Tetrapeptides and pentapeptides, their preparation and compositions containing them | RHONE-POULENC INDUSTRIES (FR) | 1988-05-03 | — | — | US | disclosed |