⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740463 | 0.76 | — | — | |
| SCHEMBL3071411 | 0.76 | — | — | |
| SCHEMBL15541066 | 0.76 | — | — | |
| SCHEMBL456126 | 0.76 | — | — | |
| SCHEMBL29413240 | 0.76 | — | — | |
| SCHEMBL11776219 | 0.73 | GRM5 (0.33) | — | |
| SCHEMBL15516427 | 0.73 | GRM5 (0.49) | — | |
| SCHEMBL16482920 | 0.73 | GRM5 (0.53) | — | |
| SCHEMBL24811641 | 0.73 | GRM5 (0.45) | — | |
| SCHEMBL2445812 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476655-B | Carbonic anhydrase IX-targeted nuclear imaging and radiotherapy agents and uses thereof | 约翰霍普金斯大学 | 2022-03-08 | — | — | CN | disclosed |
| EP-3455222-B1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-03-02 | — | — | EP | disclosed |
| US-10857246-B2 | Nuclear imaging and radiotherapeutics agents targeting carbonic anhydrase IX and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190192699-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-06-27 | — | — | US | disclosed |
| EP-3455222-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | The Johns Hopkins University (US) | 2019-03-20 | — | — | EP | disclosed |
| US-20180133348-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
| WO-2017197251-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-16 | — | — | WO | disclosed |
| WO-2016196628-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-12-08 | — | — | WO | disclosed |
| EP-2635571-B1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS | THERAVANCE BIOPHARMA R & D IP LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| US-20140051689-A1 | Polycyclic Agents for the Treatment of Respiratory Syncytial Virus Infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-02-20 | — | — | US | disclosed |
| US-8598193-B2 | Polycyclic agents for the treatment of respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2013-12-03 | — | — | US | disclosed |
| EP-2287167-A1 | Polycyclic agents for the treatment of respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2011-02-23 | — | — | EP | disclosed |
| EP-1697377-B1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENT MANAGEMENT (AU) | 2011-01-26 | — | — | EP | disclosed |
| US-20100233415-A1 | OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-1997856-A1 | OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-12-03 | — | — | EP | disclosed |
| EP-1697377-A4 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENT MANAGEMENT (AU) | 2008-03-19 | — | — | EP | disclosed |
| US-20070287700-A1 | Polycyclic agents for the treatment of respiratory syncytial virus infections | BIOTA SCIENTFIC MANAGEMENMT PTY LTD. (AU) | 2007-12-13 | — | — | US | disclosed |
| EP-1697377-A1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061513-A1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2005-07-07 | — | — | WO | disclosed |