Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096757 | 0.98 | USP2 (0.53) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL10420978 | 0.98 | USP2 (0.53) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL2139322 | 0.80 | USP2 (0.53) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL10559210 | 0.80 | USP2 (0.53) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL1841790 | 0.80 | USP2 (0.49) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL24612929 | 0.80 | USP2 (0.38) | USP2CNR2PLA2G2CVDRHTT | |
| SCHEMBL5350631 | 0.79 | USP2 (0.51) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL7867560 | 0.79 | USP2 (0.51) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL2590611 | 0.79 | USP2 (0.51) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL2467812 | 0.78 | USP2 (0.39) | USP2LMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948588-A | ETHER DERIVATIVES OF GLYCEROLS OR POLYGLYCEROLS | KAO CORPORATION (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4859696-A | Precutaneous absorption accelerator and preparation containing same | KAO CORPORATION (JP) | 1989-08-22 | — | — | US | disclosed |