Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543850 | 0.98 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10421082 | 0.97 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10422073 | 0.96 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7010393 | 0.94 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9828151 | 0.94 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9829438 | 0.93 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10610841 | 0.92 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10547291 | 0.92 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9818424 | 0.92 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7004658 | 0.92 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |