Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.77 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazinoic Acid SCHEMBL23757 | 0.88 | — | — | |
| Pyrazinoic Acid SCHEMBL29651929 | 0.88 | — | — | |
| Pyrazinoic Acid SCHEMBL8978502 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL9478203 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL8341710 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL6631652 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL8335237 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL9478226 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL623119 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL10349317 | 0.86 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962111-A | Pyrazinoic acid esters as antituberculosis agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-10-09 | — | — | US | disclosed |