Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714723 | 0.93 | CYSLTR1 (0.53) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10420754 | 0.92 | CYSLTR1 (0.55) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10421806 | 0.91 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9830483 | 0.91 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7008540 | 0.90 | CYSLTR1 (0.55) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10420744 | 0.90 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7717069 | 0.90 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10421916 | 0.89 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL9829295 | 0.88 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL8107945 | 0.88 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |