Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.94 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 4/20 | 0.36 |
| ▸ | GABRD | O14764 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL4078935 | 1.00 | — | — | |
| Valine SCHEMBL628974 | 1.00 | SLC7A5 (0.94) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL135483 | 1.00 | — | — | |
| Valine SCHEMBL6396547 | 0.97 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL288203 | 0.97 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL1813972 | 0.97 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL2785563 | 0.97 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL8516 | 0.97 | — | — | |
| Valine SCHEMBL41225 | 0.97 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL8515 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159008-B1 | USE OF ADCC-OPTIMISED ANTIBODIES FOR TREATING WEAK-RESPONSE PATIENTS | LAB FRANCAIS DU FRACTIONNEMENT (FR) | 2020-07-22 | — | — | EP | disclosed |
| EP-3159008-A1 | USE OF ADCC-OPTIMISED ANTIBODIES FOR TREATING WEAK-RESPONSE PATIENTS | Laboratoire Français du Fractionnement et des Biotechnologies (FR) | 2017-04-26 | — | — | EP | disclosed |
| EP-2275134-B1 | USE OF ADCC-OPTIMIZED ANTIBODIES FOR TREATING WEAK PATIENTS | LABORATOIRE FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES (FR) | 2017-02-15 | — | — | EP | disclosed |
| EP-1648513-B1 | USE OF ADCC-OPTIMIZED ANTIBODIES FOR TREATING PATIENTS ANSWERING WEAKLY TO ANTIBODY TREATMENT. | FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES LAB (FR) | 2014-09-24 | — | — | EP | disclosed |
| EP-2275134-A2 | Use of ADCC-optimized antibodies for treating weak patients | LFB Biotechnologies (FR) | 2011-01-19 | — | — | EP | disclosed |