Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 8/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 8/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.38 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22388691 | 1.00 | GRIA4 (0.47) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL13201930 | 0.80 | GRIA4 (0.48) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL10425786 | 0.80 | GRIA4 (0.48) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL23789393 | 0.77 | GRIA4 (0.32) | GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL17308661 | 0.76 | GRIA2 (0.46) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL5289522 | 0.75 | CYP2C19 (0.49) | GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL17002135 | 0.71 | GRIA2 (0.47) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL19065057 | 0.71 | GRIA2 (0.43) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL17293207 | 0.71 | GRIA2 (0.43) | GRIA4GRIA1GRIA3GRIA2GRIK1 | |
| SCHEMBL20272576 | 0.70 | CYP1A2 (0.42) | GRIA4GRIA1GRIA3GRIA2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898878-A | Antioxidant thiohistidine compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1990-02-06 | — | — | US | disclosed |