Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.59 |
| ▸ | RRM1 | P23921 | 1/20 | 0.58 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15659209 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15660958 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15659192 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15657338 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15658610 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15661217 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15662158 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL16414566 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15660830 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL15657340 | 1.00 | DPP7 (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031892-A1 | SPHINGOLIPID METABOLITE MIMETICS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-01-29 | — | — | US | disclosed |
| US-20150031892-A1 | SPHINGOLIPID METABOLITE MIMETICS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-01-29 | — | — | US | disclosed |
| WO-2014066613-A2 | SPHINGOLIPID METABOLITE MIMETICS | ZHEJIANG UNIVERSITY (CN) | 2014-05-01 | — | — | WO | disclosed |
| EP-0216832-B1 | NOVEL INSULIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES | NOVO NORDISK A/S (DK) | 1990-08-29 | — | — | EP | disclosed |
| EP-0216832-A1 | NOVEL INSULIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES. | NORDISK GENTOFTE (DK) | 1987-04-08 | — | — | EP | disclosed |
| WO-1986005496-A1 | NOVEL INSULIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES | NORDISK GENTOFTE A/S (DK) | 1986-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031892-A1 | SPHINGOLIPID METABOLITE MIMETICS | BID, BAD, S1PR1 | DPP7 3498/4885RRM1 706/4885GNAI3 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.