Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682933 | 1.00 | HTT (1.00) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL10428187 | 1.00 | HTT (1.00) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8962574 | 1.00 | HTT (1.00) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8678901 | 1.00 | HTT (1.00) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL1309117 | 1.00 | HTT (1.00) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL9952684 | 1.00 | HTT (1.00) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL11467186 | 0.99 | HTT (0.97) | HTTPOLBAPEX1TDP1TSHR | |
| Hydrochloric Acid SCHEMBL6450158 | 0.99 | HTT (0.97) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL2034725 | 0.98 | HTT (0.97) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL9105115 | 0.96 | HTT (0.92) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925589-A | ADDITION ACRYLIC TYPE POLYMER | HOFFMANN-LA ROCHE INC. (US) | 1990-05-15 | — | — | US | disclosed |
| US-4293435-A | ACRYLATE POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |