Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259043 | 0.86 | KMT2A (0.75) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| Pacrinolol SCHEMBL1255309 | 0.84 | KMT2A (0.66) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| Pacrinolol SCHEMBL7266361 | 0.84 | KMT2A (0.66) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| Pacrinolol SCHEMBL10429388 | 0.84 | KMT2A (0.66) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| Pacrinolol SCHEMBL29763761 | 0.84 | KMT2A (0.66) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| Pacrinolol SCHEMBL10429425 | 0.83 | KMT2A (0.68) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7287594 | 0.82 | KMT2A (0.66) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL10555388 | 0.82 | KMT2A (0.75) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL10554140 | 0.82 | KMT2A (0.75) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL11092630 | 0.81 | KMT2A (0.44) | KMT2AADRB2ADRB1HTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952730-A | Process for inverting the configuration of optically active compounds, and optically active intermediates produced in this process | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |