Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 19/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enviradene SCHEMBL29367493 | 1.00 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL146323 | 1.00 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL10429408 | 1.00 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145535 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11147979 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145549 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11155088 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145881 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145539 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145546 | 0.91 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424362-A | Process for preparing a trans-6-propenyl benzimidazole | ELI LILLY AND COMPANY (US) | 1984-01-03 | — | — | US | claimed |
| US-4956351-A | INCLUSION COMPLEXESOFVIRICIDES; RHINITIS; SUSTAINED RELEASE; NONIRRITATING TO MUCOUS MEMBRANE | JANSSEN PHARMACEUTICA N.V. FRAME-543 (BE) | 1990-09-11 | — | — | US | disclosed |
| EP-0300526-A2 | Antiviral pharmaceutical compositions containing cyclodextrins | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-25 | — | — | EP | disclosed |
| US-4463181-A | REACTING WITH ALKALI METAL HYDROXIDE OR CARBONATE | ELI LILLY AND COMPANY (US) | 1984-07-31 | — | — | US | disclosed |
| US-4424362-A | Process for preparing a trans-6-propenyl benzimidazole | ELI LILLY AND COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4424362-A | Process for preparing a trans-6-propenyl benzimidazole | ELI LILLY AND COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4420479-A | 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES | ELI LILLY AND COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| EP-0091794-A1 | Process for preparing 1.6-disubstituted 2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |