Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | EPOR | P19235 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491987 | 0.89 | EPOR (0.51) | EPOR | |
| SCHEMBL3776750 | 0.89 | EPOR (0.51) | EPOR | |
| SCHEMBL22804052 | 0.89 | EPOR (0.51) | EPOR | |
| SCHEMBL4357291 | 0.89 | EPOR (0.46) | MC4RRAB9AEPORNPC1TDP1 | |
| SCHEMBL9818005 | 0.85 | ANPEP (0.46) | RAB9ATDP1TGM2ATMITGA4 | |
| SCHEMBL10477497 | 0.85 | EPOR (0.46) | EPORTDP1 | |
| SCHEMBL4852056 | 0.85 | EPOR (0.46) | EPORTDP1 | |
| SCHEMBL9574165 | 0.85 | EPOR (0.46) | EPORTDP1 | |
| SCHEMBL3222447 | 0.84 | EPOR (0.52) | EPOR | |
| SCHEMBL30605860 | 0.82 | EPOR (0.42) | MC4RRAB9AEPORNPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362002-A1 | HIV protease inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |