SCHEMBL1043345

SCHEMBL1043345

O=Cc1ccncc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957536 1.00
SCHEMBL28494457 0.98 ERN1 (0.47)
SCHEMBL1042172 0.82
SCHEMBL29955436 0.78 KMT2A (0.46)
SCHEMBL2600757 0.78 KMT2A (0.46)
SCHEMBL16919129 0.77
SCHEMBL30570000 0.74
SCHEMBL526587 0.74
Formic Acid SCHEMBL27564133 0.74 ERN1 (0.44)
SCHEMBL25320343 0.74 CCNT1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084452-A1 BIOLOGICAL INDICATOR FOR DETERMINING THE EFFICACY OF A STERILIZATION PROCESS AND METHODS OF USE TERRAGENE LLC 2025-03-13 US claimed
US-11970475-B1 4-(1-(2-Hydroxypropyl)-4,5-diphenyl-1H-imidazol-2-yl)pyridin-3-ol as an antimicrobial compound King Faisal University (SA) 2024-04-30 US claimed
CN-116574139-A NHCs-Pd complex with ultraviolet-visible light controllable isomerization and catalytic activity and preparation method thereof 上海师范大学 2023-08-11 CN claimed
CN-109761964-B Coumarin-3-hydroxypyridine-4-one derivative, and preparation method and application thereof 浙江工业大学 2021-02-02 CN claimed
CN-108358837-B Synthesis method of hydroxyl pyridone compound containing amino 浙江工业大学 2020-11-13 CN claimed
EP-2275412-A1 Indole and benzimidazole derivatives Novartis Vaccines and Diagnostics, Inc. (US) 2011-01-19 EP claimed
US-7608723-B2 N-(3-aminopropyl)-N-[(1R)-1-(1-benzyl-1H-benzimidazol-2-yl)-2-methylpropyl]-4-chlorobenzamide;kinesin spindle protein modulators; anticarcinogenic agents; in vivo stability, bio-availability; diagnosis/medical/;antitumor agents hyperplasia; restinosis; antiinflammatory agents; cardiac hypertrophy NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2009-10-27 US claimed
US-20080317744-A1 Indole and Benzimidazole Derivatives CHIRON CORPORATION (US) 2008-12-25 US claimed
EP-1807399-A2 INDOLE AND BENZIMIDAZOLE DERIVATIVES Novartis Vaccines and Diagnostics, Inc. (US) 2007-07-18 EP claimed
WO-2006049835-A2 INDOLE AND BENZIMIDAZOLE DERIVATIVES NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) 2006-05-11 WO claimed
US-7037654-B2 Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents ACLARA BIOSCIENCES, INC. (US) 2006-05-02 US claimed
US-20060084687-A1 Indole and benzimidazole derivatives NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2006-04-20 US claimed
US-20050053939-A1 Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents MONOGRAM BIOSCIENCES, INC. 2005-03-10 US claimed
WO-2003042658-A2 METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS ACLARA BIOSCIENCES, INC. (US) 2003-05-22 WO claimed
EP-4695306-A2 SINGLE-DOMAIN ANTIBODIES THAT BIND THE CONSTANT REGION OF IMMUNOGLOBULINS Oregon Health & Science University (US) 2026-02-18 EP disclosed
WO-2025128834-A1 AKT1 MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
US-20250127801-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2025-04-24 US disclosed
US-20040096825-A1 METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS ACLARA BIOSCIENCES, INC. 2004-05-20 US disclosed
WO-2004019889-A2 INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS BIOSTRATUM, INC. (US) 2004-03-11 WO disclosed
WO-2003042658-A2 METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS ACLARA BIOSCIENCES, INC. (US) 2003-05-22 WO disclosed