Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25198959 | 0.83 | HTR2A (0.58) | HTR2AHTR2CHTR2BPKMMAPT | |
| SCHEMBL17631815 | 0.83 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAPTMEN1 | |
| SCHEMBL17632850 | 0.83 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAPTLMNA | |
| SCHEMBL25196369 | 0.83 | HTR2A (0.62) | HTR2AHTR2CHTR2BMAPTMEN1 | |
| SCHEMBL10434133 | 0.83 | HTR2A (0.58) | HTR2AHTR2CHTR2BPKMMAPT | |
| SCHEMBL19031388 | 0.83 | HTR2A (0.57) | HTR2AHTR2CHTR2BPKMMAPT | |
| SCHEMBL25191480 | 0.83 | HTR2A (0.54) | HTR2AHTR2CHTR2BPKMACHE | |
| SCHEMBL9158986 | 0.82 | HTR2A (0.57) | HTR2AHTR2CHTR2BMAPTSMN1; SMN2 | |
| SCHEMBL25219944 | 0.81 | HTR2A (0.67) | HTR2AHTR2CHTR2BPKMMAPT | |
| SCHEMBL25198136 | 0.81 | HTR2A (0.56) | HTR2AHTR2CHTR2BPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399358-A2 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |