SCHEMBL10434992

SCHEMBL10434992

CCCCCC[C@H]1CC[C@](C(=O)O)(C2(C(=O)O)CCCCC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
TP53 P04637 1/20 0.41
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX5 P09917 1/20 0.38
GPR119 Q8TDV5 1/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 1/20 0.37
NAAA Q02083 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTPN1 P18031 1/20 0.35
ACP1 P24666 1/20 0.35
CDC25B P30305 1/20 0.35
KDM5A P29375 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10435379 1.00 CYP1A2 (0.43) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL10435170 1.00 CYP1A2 (0.43) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL10435377 1.00 CYP1A2 (0.43) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL10435171 1.00 CYP1A2 (0.43) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL10435336 0.98 CYP1A2 (0.44) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL9797584 0.95 CYP1A2 (0.50) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL10435376 0.94 CYP1A2 (0.50) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL8724287 0.88 CYP1A2 (0.41) CYP1A2TP53MEN1HTTKMT2A
SCHEMBL10435375 0.87 CYP1A2 (0.35) CYP1A2MEN1KMT2AGPR119MAPT
SCHEMBL10435373 0.80 CYP2C19 (0.35) CYP1A2MEN1KMT2ACYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0394906-A2 Liquid crystalline composition MERCK PATENT GmbH (DE) 1990-10-31 EP disclosed