Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 6/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218750 | 0.91 | NOTUM (0.41) | GRM2IDH1NOTUM | |
| SCHEMBL8115890 | 0.91 | NOTUM (0.41) | GRM2IDH1NOTUM | |
| SCHEMBL8123321 | 0.82 | SMN1; SMN2 (0.39) | GRM2IDH1NOTUM | |
| SCHEMBL9845302 | 0.80 | HSP90AA1 (0.40) | IDH1NOTUM | |
| SCHEMBL29950062 | 0.75 | NOTUM (0.41) | GRM2IDH1NOTUMPIK3CAMTOR | |
| SCHEMBL5604547 | 0.74 | IDH1 (0.55) | GRM2IDH1PIK3CAMTOR | |
| SCHEMBL5604553 | 0.74 | IDH1 (0.55) | GRM2IDH1PIK3CAMTOR | |
| SCHEMBL21582050 | 0.73 | HDAC1 (0.47) | FAAHHDAC1 | |
| SCHEMBL9453178 | 0.73 | HDAC1 (0.47) | FAAHHDAC1 | |
| SCHEMBL9453176 | 0.73 | HDAC1 (0.47) | FAAHHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352781-A2 | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-01-31 | — | — | EP | disclosed |