Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.60 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732649 | 0.89 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DPRSS12 | |
| SCHEMBL10435864 | 0.88 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10435858 | 0.88 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL10435854 | 0.88 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DPRSS12 | |
| SCHEMBL10435871 | 0.88 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPRSS12 | |
| SCHEMBL10435886 | 0.87 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL9732552 | 0.87 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DPRSS12 | |
| SCHEMBL7716260 | 0.85 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPRSS12 | |
| SCHEMBL10435877 | 0.85 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPRSS12 | |
| SCHEMBL10435909 | 0.85 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |