Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | PI4KA | P42356 | 4/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADA | P00813 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | AHCY | P23526 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436009 | 1.00 | BCHE (0.52) | BCHEADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL23211665 | 0.84 | ADORA1 (0.46) | BCHEADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL9850184 | 0.84 | BCHE (0.53) | BCHEADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL9850186 | 0.84 | BCHE (0.53) | BCHEADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL13998327 | 0.83 | BCHE (0.56) | BCHEADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL26068423 | 0.83 | POLB (0.56) | ADORA1TP53ADORA2AAHCYNT5E | |
| SCHEMBL22327447 | 0.83 | POLB (0.56) | ADORA1TP53ADORA2AAHCYNT5E | |
| SCHEMBL7623380 | 0.83 | POLB (0.56) | ADORA1TP53ADORA2AAHCYNT5E | |
| SCHEMBL30473748 | 0.83 | POLB (0.56) | ADORA1TP53ADORA2AAHCYNT5E | |
| SCHEMBL15948689 | 0.82 | ADORA1 (0.44) | BCHEADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352248-A1 | Nucleoside derivatives | Medivir Aktiebolag (SE) | 1990-01-24 | — | — | EP | disclosed |