Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.69 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.61 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.61 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.61 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437111 | 1.00 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2ABCC1MEN1ABCB11 | |
| SCHEMBL9755780 | 0.99 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2ABCC1MEN1ABCB11 | |
| SCHEMBL9755778 | 0.93 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2ABCC1MEN1ABCB11 | |
| SCHEMBL9755782 | 0.93 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2ABCC1MEN1ABCB11 | |
| SCHEMBL9204404 | 0.92 | ABCC1 (0.68) | CYSLTR1CYSLTR2ABCC1MEN1ABCB11 | |
| SCHEMBL9204399 | 0.92 | ABCC1 (0.68) | CYSLTR1CYSLTR2ABCC1MEN1ABCB11 | |
| SCHEMBL8499103 | 0.89 | MEN1 (0.64) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A | |
| SCHEMBL8500914 | 0.89 | MEN1 (0.64) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A | |
| SCHEMBL8499107 | 0.89 | MEN1 (0.64) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A | |
| SCHEMBL8500937 | 0.89 | MEN1 (0.63) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399818-A1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC. (CA) | 1990-11-28 | — | — | EP | claimed |