Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554642 | 1.00 | HMGCR (0.46) | HMGCR | |
| SCHEMBL10554637 | 1.00 | HMGCR (0.46) | HMGCR | |
| SCHEMBL10437586 | 1.00 | HMGCR (0.46) | HMGCR | |
| SCHEMBL10552767 | 1.00 | HMGCR (0.46) | HMGCR | |
| SCHEMBL10550364 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL10550356 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL10550351 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL10550361 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL10550373 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL6905038 | 0.75 | HMGCR (0.48) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355820-A1 | Antihypercholesterolemic tetrazol-1-yl compounds | Bristol-Myers Squibb Company (US) | 1990-02-28 | — | — | EP | claimed |
| US-4870187-A | ANTILIPEMIC, ATHEROSCLEROSIS | BRISTOL-MYERS COMPANY (US) | 1989-09-26 | — | — | US | claimed |