Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768124 | 0.76 | MAPT (0.33) | MAPTKDM4EPDK2PDE2AACACB | |
| SCHEMBL6258555 | 0.75 | PDE2A (0.39) | MAPTPDK2PDE2AACACBGAA | |
| SCHEMBL9218664 | 0.73 | MAPT (0.47) | MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL9217501 | 0.73 | MAPT (0.45) | MAPTKDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL9704795 | 0.71 | MAPT (0.47) | MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL9704229 | 0.71 | MAPT (0.47) | MAPTKDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL9218168 | 0.71 | MAPT (0.43) | MAPTKDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL9215595 | 0.70 | MAPT (0.46) | MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL8346846 | 0.68 | PDK2 (0.51) | MAPTKDM4EPDK2PDE2ALMNA | |
| SCHEMBL9704767 | 0.68 | PDE2A (0.37) | MAPTKDM4EPDK2PDE2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350237-A2 | Triazole insecticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-01-10 | — | — | EP | disclosed |