Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | PI4KA | P42356 | 2/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | AHCY | P23526 | 6/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864727 | 0.89 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL3408365 | 0.86 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL11703712 | 0.86 | ADORA2A (0.54) | ADORA2AADORA3AHCYADORA2BADORA1 | |
| SCHEMBL6299609 | 0.86 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL6298549 | 0.85 | ADORA2A (0.53) | ADORA2AADORA3AHCYADORA2BADORA1 | |
| SCHEMBL3409898 | 0.85 | ADORA2A (0.53) | ADORA2AADORA3AHCYADORA2BADORA1 | |
| SCHEMBL11701245 | 0.84 | ADORA2A (0.53) | ADORA2AADORA3AHCYADORA2BADORA1 | |
| SCHEMBL3409866 | 0.81 | ADA (0.51) | ADORA2AADORA3SMN1; SMN2 | |
| SCHEMBL3411985 | 0.81 | ADORA2A (0.53) | ADORA2AADORA3AHCYADORA2BMEN1 | |
| SCHEMBL1078828 | 0.81 | ADORA2A (0.64) | ADORA2AADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358536-A2 | Novel S-adenosyl methionine decarboxylase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1990-03-14 | — | — | EP | disclosed |