Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605472 | 0.98 | RNPEP (0.55) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL18193482 | 0.98 | RNPEP (0.55) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL8928051 | 0.81 | RNPEP (0.54) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL29456085 | 0.81 | RNPEP (0.54) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL5179360 | 0.80 | RNPEP (0.48) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL5179354 | 0.80 | RNPEP (0.48) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL164056 | 0.79 | RNPEP (0.52) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL748892 | 0.79 | RNPEP (0.52) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL76427 | 0.79 | RNPEP (0.52) | RNPEPLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL30975661 | 0.79 | RNPEP (0.52) | RNPEPLMNAALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355784-A1 | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0355784-A1 | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |