Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944860 | 0.95 | HMGCR (0.42) | HMGCR | |
| SCHEMBL6944857 | 0.95 | HMGCR (0.42) | HMGCR | |
| SCHEMBL10442265 | 0.84 | HMGCR (0.60) | HMGCR | |
| SCHEMBL6944717 | 0.83 | HMGCR (0.40) | HMGCR | |
| SCHEMBL6944721 | 0.83 | HMGCR (0.40) | HMGCR | |
| SCHEMBL10637080 | 0.83 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9441787 | 0.81 | PTGDR2 (0.33) | HMGCR | |
| SCHEMBL9441790 | 0.81 | PTGDR2 (0.33) | HMGCR | |
| SCHEMBL6944852 | 0.80 | HMGCR (0.41) | HMGCR | |
| SCHEMBL10442012 | 0.80 | HMGCR (0.41) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401705-A2 | Use of an HMG CoA reductase inhibitor and/or a squalene synthetase inhibitor for treating peripheral atherosclerotic disease | E.R. Squibb & Sons, Inc. (US) | 1990-12-12 | — | — | EP | disclosed |