SCHEMBL10442292

SCHEMBL10442292

Nc1ccccc1C1CO1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALOX15 P16050 2/20 0.41
CYP3A4 P08684 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TAAR1 Q96RJ0 2/20 0.35
GID4 Q8IVV7 1/20 0.34
HTR2A P28223 1/20 0.33
PARP1 P09874 1/20 0.32
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4846202 0.84 MAPKAPK2 (0.35) TSHRALOX15CYP3A4CASP1CASP7
SCHEMBL18849381 0.82 TSHR (0.36) TSHRALOX15CYP3A4CASP1CASP7
SCHEMBL37732 0.82 TSHR (0.57) TSHRNOS3NOS1NOS2HTR2A
SCHEMBL10323402 0.77 CFTR (0.38) TSHRALOX15CYP3A4CASP1CASP7
SCHEMBL10324942 0.77 CFTR (0.38) TSHRALOX15CYP3A4CASP1CASP7
SCHEMBL10323447 0.77 CFTR (0.38) TSHRALOX15CYP3A4CASP1CASP7
SCHEMBL28134090 0.76 TSHR (0.42) TSHRCYP3A4ALDH1A1L3MBTL1TAAR1
SCHEMBL28109304 0.76 GAA (0.37) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL5485539 0.74 NSD2 (0.40) TSHRALOX15CYP3A4CASP1CASP7
SCHEMBL20216424 0.74 CYP3A4 (0.39) TSHRALOX15CYP3A4CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012095796-A1 ORGANIC PHOTOVOLTAIC DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2012-07-19 WO disclosed
US-7449602-B2 Stilbene derivative compound, process for producing the same, and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2008-11-11 US disclosed