Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444570 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL1982627 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL428191 | 0.83 | PIK3CA (0.42) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL8027812 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL11621741 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL11621739 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL11540675 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL11540672 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1CTSLNPSR1 | |
| SCHEMBL17146135 | 0.78 | MEN1 (0.40) | KDM4EALDH1A1L3MBTL1MAPTPKM | |
| SCHEMBL13167842 | 0.78 | MEN1 (0.40) | KDM4EALDH1A1L3MBTL1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400403-A2 | N-aryl-nitrogen-heterocycles | BAYER AG (DE) | 1990-12-05 | — | — | EP | disclosed |