Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28842567 | 0.81 | DAO (0.43) | DAOADORA3LMNASMN1; SMN2HPGD | |
| SCHEMBL191244 | 0.78 | HPGD (0.46) | DAOLMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL30275232 | 0.78 | HPGD (0.46) | DAOLMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL8482902 | 0.78 | KDM4E (0.50) | LMNASMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL21660652 | 0.77 | NPC1 (0.58) | PDE3BPDE3AGUSBLMNASMN1; SMN2 | |
| Iodide SCHEMBL8481287 | 0.77 | HPGD (0.45) | DAOLMNASMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL8478843 | 0.77 | HPGD (0.45) | DAOLMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL9480103 | 0.76 | PARP1 (0.43) | PDE3BPDE3ADAOADORA3ADORA1 | |
| SCHEMBL9231917 | 0.75 | PDE3B (0.52) | PDE3BPDE3AGUSBDAOADORA3 | |
| Sulfuric Acid SCHEMBL28570474 | 0.75 | HPGD (0.41) | LMNASMN1; SMN2HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160175-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-0376166-A1 | Condensed quinoline system compound and process of preparation thereof | MECT CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |