Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560171 | 0.92 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1PPARGPPARAPTGES | |
| SCHEMBL9560036 | 0.92 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1PPARGPPARAPTGES | |
| SCHEMBL10448298 | 0.88 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PPARGPPARAPTGES | |
| SCHEMBL10448473 | 0.86 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PPARGPPARAPTGES | |
| SCHEMBL9560309 | 0.79 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL9560112 | 0.78 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL9559867 | 0.74 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1PLA2G4BLMNAMAPT | |
| SCHEMBL9560190 | 0.73 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1PPARGPPARA | |
| SCHEMBL9560087 | 0.73 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1PPARGPPARA | |
| SCHEMBL9559989 | 0.73 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358240-A2 | Intermediates for the preparation of leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-03-14 | — | — | EP | disclosed |