SCHEMBL10448644

SCHEMBL10448644

Cc1cc(/N=N/c2c(S(=O)(=O)O)cc3cc(S(=O)(=O)O)cc(N)c3c2O)ccc1/N=N/c1ccc2ccccc2c1S(=O)(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.68
HTT P42858 1/20 0.68
KMT2A Q03164 1/20 0.68
PHLPP2 Q6ZVD8 2/20 0.68
ENPP2 Q13822 7/20 0.56
CYP1A2 P05177 2/20 0.55
MAPK1 P28482 2/20 0.55
CYP2C9 P11712 1/20 0.55
DNASE1L3 Q13609 1/20 0.55
USP2 O75604 1/20 0.52
PTPN1 P18031 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PRMT1 Q99873 1/20 0.46
SENP2 Q9HC62 3/20 0.45
SENP1 Q9P0U3 3/20 0.45
SENP3 Q9H4L4 2/20 0.45
SUMO2 P61956 1/20 0.45
SUMO1 P63165 1/20 0.45
SENP7 Q9BQF6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172980 1.00 MEN1 (0.68) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL6028561 0.92 PHLPP2 (0.65) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL6028562 0.92 PHLPP2 (0.65) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL9179796 0.87 MEN1 (0.77) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL10448639 0.87 MEN1 (0.77) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL13763562 0.86 CYP1A2 (0.64) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL9174934 0.86 CYP1A2 (0.62) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL10448356 0.86 CYP1A2 (0.62) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL14647836 0.82 MEN1 (0.69) MEN1HTTKMT2APHLPP2ENPP2
SCHEMBL7588620 0.82 PHLPP2 (0.64) MEN1HTTKMT2APHLPP2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400648-A1 Polyazo dye compounds having plural vinylsulfone type fiber reactive groups in one molecule SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 EP disclosed