⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018178 | 1.00 | — | — | |
| SCHEMBL7416325 | 0.79 | — | — | |
| SCHEMBL3761305 | 0.79 | — | — | |
| SCHEMBL17234507 | 0.79 | — | — | |
| SCHEMBL14159545 | 0.78 | TSHR (0.43) | — | |
| Hydrochloric Acid SCHEMBL7497528 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7497539 | 0.77 | — | — | |
| SCHEMBL18389660 | 0.77 | — | — | |
| SCHEMBL10519890 | 0.76 | — | — | |
| SCHEMBL7397717 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150209339-A1 | Hetero-Substituted Acetanilide Derivatives As Analgesic Agents | JANSSEN PHARMACEUTICA, N.V. (BE) | 2015-07-30 | — | — | US | disclosed |
| US-9018241-B2 | Hetero-substituted acetanilide derivatives as analgesic agents | JANSSEN PHARMACEUTICA, NV (BE) | 2015-04-28 | — | — | US | disclosed |
| US-20130109863-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATIVES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-05-02 | — | — | US | disclosed |
| US-8357715-B2 | Hetero-substituted acetanilide derivatives as analgesic agents | JANSSEN PHARMACEUTICA, NV (BE) | 2013-01-22 | — | — | US | disclosed |
| US-20120129763-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2011140009-A1 | METHODS OF USING SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| EP-2373694-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BioMarin Pharmaceutical Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| US-20110015119-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| EP-2238102-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | Lead Therapeutics, Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| US-20100204284-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATIVES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-08-12 | — | — | US | disclosed |
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-7718692-B2 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-05-18 | — | — | US | disclosed |
| WO-2009085562-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2005084663-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA N.V. (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050182108-A1 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-18 | — | — | US | disclosed |
| US-4036957-A | Phenoxy compounds in combinations to suppress gastric bleeding in aspirin therapy | A. H. ROBINS COMPANY, INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-4036957-A | Phenoxy compounds in combinations to suppress gastric bleeding in aspirin therapy | A. H. ROBINS COMPANY, INC. (US) | 1977-07-19 | — | — | US | disclosed |