Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862588 | 0.84 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL10639273 | 0.73 | — | — | |
| SCHEMBL5358039 | 0.66 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL5367335 | 0.66 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL5353460 | 0.66 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL5359563 | 0.66 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL10672680 | 0.65 | — | — | |
| SCHEMBL9862532 | 0.65 | ESR1 (0.42) | ESR1ESR2 | |
| SCHEMBL10596570 | 0.65 | CA12 (0.35) | ESR1ESR2 | |
| SCHEMBL9580333 | 0.64 | ESR1 (0.46) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |