Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379723 | 1.00 | MAPT (0.45) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL6892060 | 1.00 | MAPT (0.45) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL6659847 | 0.98 | MAPT (0.44) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL28162721 | 0.98 | MAPT (0.44) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL6655041 | 0.98 | MAPT (0.44) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL10699044 | 0.98 | MAPT (0.44) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL6656073 | 0.98 | MAPT (0.44) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL11375368 | 0.98 | TLR8 (0.44) | MAPTTYRCYP3A4TSHRMEN1 | |
| SCHEMBL1023150 | 0.97 | TLR8 (0.43) | MAPTTYRCYP3A4TSHRMEN1 | |
| Bromide SCHEMBL27710135 | 0.97 | TLR8 (0.43) | MAPTTYRCYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943656-A | SULFONATION OF POLYALKYLAROMATIC COMPOUNDS, SEPARATION INTO LAYERED LIQUID PHASES | KING INDUSTRIES, INC. (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0168778-B1 | PROCESS FOR THE PRODUCTION OF POLYALKYLAROMATIC POLYSULFONIC ACIDS AND RECOVERY BY HEAVY PHASE SEPARATION | KING INDUSTRIES, INC. (US) | 1988-11-23 | — | — | EP | disclosed |
| EP-0168778-A2 | Process for the production of polyalkylaromatic polysulfonic acids and recovery by heavy phase separation | KING INDUSTRIES, INC. (US) | 1986-01-22 | — | — | EP | disclosed |