SCHEMBL1045331

SCHEMBL1045331

Fc1c(Cl)[c]c(Cl)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942965 0.83
SCHEMBL2461438 0.81
SCHEMBL10776194 0.78
SCHEMBL8571670 0.74
SCHEMBL1392210 0.69
SCHEMBL6568309 0.67
SCHEMBL8733884 0.67
SCHEMBL2464341 0.65
SCHEMBL1361208 0.65
SCHEMBL7662173 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190730-A1 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS PHARMACEUTICAL AGENT JAPAN TOBACCO INC. (JP) 2023-06-22 US disclosed
US-11597817-B2 Thermoplastic resin composition, method of producing thermoplastic resin composition, molded article of cellulose-reinforced resin, and method of producing molded article of cellulose-reinforced resin FURUKAWA ELECTRIC CO., LTD (JP) 2023-03-07 US disclosed
US-11597818-B2 Molded article FURUKAWA ELECTRIC CO., LTD. (JP) 2023-03-07 US disclosed
EP-3438186-B1 THERMOPLASTIC RESIN COMPOSITION, THERMOPLASTIC RESIN COMPOSITION PRODUCTION METHOD, CELLULOSE-REINFORCED RESIN MOLDED PRODUCT, AND CELLULOSE-REINFORCED RESIN MOLDED PRODUCT MANUFACTURING METHOD FURUKAWA ELECTRIC CO LTD (JP) 2023-02-22 EP disclosed
EP-3438207-B1 THERMOPLASTIC RESIN COMPOSITION, THERMOPLASTIC RESIN COMPOSITION PRODUCTION METHOD, CELLULOSE-REINFORCED RESIN MOLDED PRODUCT, AND CELLULOSE-REINFORCED RESIN MOLDED PRODUCT MANUFACTURING METHOD FURUKAWA ELECTRIC CO LTD (JP) 2023-02-15 EP disclosed
US-11578192-B2 Molded article FURUKAWA ELECTRIC CO., LTD. (JP) 2023-02-14 US disclosed
US-11530316-B2 2022-12-20 US disclosed
EP-3689974-A1 MOLDED ARTICLE Furukawa Electric Co., Ltd. (JP) 2020-08-05 EP disclosed
EP-3689972-A1 MOLDED ARTICLE Furukawa Electric Co., Ltd. (JP) 2020-08-05 EP disclosed
US-20200224007-A1 MOLDED ARTICLE FURUKAWA ELECTRIC CO., LTD. (JP) 2020-07-16 US disclosed
EP-2033954-A1 6-(HETEROCYCLE-SUBSTITUTED BENZYL)-4-OXOQUINOLINE COMPOUND AND USE OF THE SAME AS HIV INTEGRASE INHIBITOR Japan Tobacco, Inc. (JP) 2009-03-11 EP disclosed
US-20090036684-A1 METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND SHIONOGI & CO., LTD. (JP) 2009-02-05 US disclosed
EP-1992607-A1 METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND Japan Tobacco, Inc. (JP) 2008-11-19 EP disclosed
US-20080207618-A1 6- (Heterocyclyl-substituted Benzyl) -4-Oxoquinoline Compound and Use Thereof as HIV Integrase Inhibitor JAPAN TOBACCO INC. (JP) 2008-08-28 US disclosed
US-7176220-B2 4-oxoquinoline compound and use thereof as pharmaceutical agent JAPAN TOBACCO INC. (JP) 2007-02-13 US disclosed
US-20060217413-A1 4-Oxoquinoline compound and use thereof as HIV integrase inhibitor JAPAN TOBACCO INC. 2006-09-28 US disclosed
US-20060084665-A1 Quinolizinone compound and use thereof as HIV integrase inhibitor JAPAN TOBACCO INC. (JP) 2006-04-20 US disclosed
US-20050239819-A1 4-Oxoquinoline compounds and utilization thereof as hiv integrase inhibitors SHIONOGI & CO., LTD. (JP) 2005-10-27 US disclosed
EP-1564210-A1 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS JAPAN TOBACCO INC. (JP) 2005-08-17 EP disclosed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed