Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10234002 | 0.95 | NPC1 (0.43) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL12912337 | 0.92 | NPC1 (0.42) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL16063431 | 0.86 | NPC1 (0.47) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL14845526 | 0.85 | NPC1 (0.34) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL14845527 | 0.84 | NPC1 (0.36) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL10456879 | 0.83 | NPC1 (0.42) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL14878323 | 0.82 | KDM5A (0.33) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL10234001 | 0.82 | NPC1 (0.56) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL10278308 | 0.81 | NPC1 (0.44) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL16328107 | 0.81 | NPC1 (0.43) | NPC1RAB9AHPGDTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222326-B2 | Water-based ink composition for inkjet recording | FUJIFILM CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100160504-A1 | WATER-BASED INK COMPOSITION FOR INKJET RECORDING | FUJIFILM CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |