⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8863481 | 0.97 | CYP19A1 (0.39) | — | |
| SCHEMBL8864046 | 0.85 | CYP19A1 (0.34) | — | |
| SCHEMBL12925977 | 0.78 | ATM (0.33) | — | |
| SCHEMBL19756421 | 0.78 | PRMT5 (0.40) | — | |
| SCHEMBL23119198 | 0.77 | CYP19A1 (0.38) | — | |
| SCHEMBL13863261 | 0.77 | — | — | |
| SCHEMBL4313822 | 0.77 | — | — | |
| SCHEMBL24683919 | 0.77 | — | — | |
| SCHEMBL8657854 | 0.77 | — | — | |
| SCHEMBL8282844 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2041 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924976-A | Diaryl heterocyclic amine compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-10-24 | — | — | CN | claimed |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | TANGO THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | TANGO THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240239764-A1 | SUBSTITUTED AMINOBENZYL HETEROARYL COMPOUNDS AS EGFR AND/OR PI3K INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-07-18 | — | — | US | disclosed |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240239811-A1 | 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T | REMIX THERAPEUTICS INC. | 2024-07-18 | — | — | US | disclosed |
| WO-2024151833-A1 | SPIRO DERIVATIVES AS M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240239835-A9 | NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239835-A9 | NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-7157492-B2 | Dibenzo chromene derivatives and their use as ERβ selective ligands | WYETH (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157486-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2007-01-02 | — | — | US | disclosed |
| US-20060281763-A1 | Carboxamide inhibitors of TGFbeta | SCIOS INC. | 2006-12-14 | — | — | US | disclosed |
| WO-2006105222-A2 | CARBOXAMIDE INHIBITORS OF TGFB | SCIOS INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-0212822-A1 | A composition containing a plant growth regulator and an alkanol and a method of using the same | ICI AMERICAS INC. (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |