Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693074 | 1.00 | SLC2A1 (0.69) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9692361 | 0.92 | SLC2A1 (0.57) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9693016 | 0.92 | SLC2A1 (0.57) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9693193 | 0.90 | SLC2A1 (0.55) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9693199 | 0.90 | SLC2A1 (0.55) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9690674 | 0.85 | LCK (0.53) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9692105 | 0.85 | LCK (0.53) | SLC2A1MAOAMAOBHRH3ALOX5 | |
| SCHEMBL9693038 | 0.82 | SLC2A1 (0.89) | SLC2A1MAOB | |
| SCHEMBL9692993 | 0.82 | SLC2A1 (0.89) | SLC2A1MAOB | |
| SCHEMBL9693042 | 0.82 | SLC2A1 (0.89) | SLC2A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170524-A2 | Nitrogen containing heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-05 | — | — | EP | claimed |
| US-4968698-A | FUNGICIDES, ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0170524-A2 | Nitrogen containing heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-05 | — | — | EP | disclosed |