Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 18/20 | 0.83 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458010 | 1.00 | PTAFR (0.83) | PTAFRTAS1R3TAS1R1USP2ALDH1A1 | |
| SCHEMBL10459177 | 0.91 | PTAFR (0.83) | PTAFRUSP2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10459516 | 0.91 | PTAFR (0.83) | PTAFRUSP2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10459654 | 0.91 | PTAFR (1.00) | PTAFRUSP2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10459655 | 0.91 | PTAFR (1.00) | PTAFRUSP2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10459863 | 0.91 | PTAFR (0.81) | PTAFRTAS1R3TAS1R1USP2ALDH1A1 | |
| SCHEMBL10459864 | 0.91 | PTAFR (0.81) | PTAFRTAS1R3TAS1R1USP2ALDH1A1 | |
| SCHEMBL10459238 | 0.91 | PTAFR (1.00) | PTAFRUSP2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10459706 | 0.91 | PTAFR (1.00) | PTAFRUSP2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10458061 | 0.89 | PTAFR (1.00) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916145-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1990-04-10 | — | — | US | disclosed |