Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458381 | 0.95 | CA12 (0.59) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL12354082 | 0.91 | TDP1 (0.68) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL14589126 | 0.84 | CYP2A6 (0.50) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL9985738 | 0.84 | CA12 (0.50) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL12027092 | 0.84 | CA12 (0.50) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL14764547 | 0.84 | CA12 (0.50) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL10457893 | 0.83 | CYP17A1 (0.48) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL14769328 | 0.82 | MAPT (0.49) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL8361854 | 0.82 | CA1 (0.56) | CA12CA1CA9TDP1KDM4E | |
| SCHEMBL30498736 | 0.82 | CA1 (0.56) | CA12CA1CA9TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |