Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919402 | 0.95 | NCEH1 (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL236078 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL734929 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL284188 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL11381159 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL283786 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL234512 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL284699 | 0.93 | TYR (0.47) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL7123136 | 0.93 | NCEH1 (0.49) | KDM4EALDH1A1GAAHPGDNCEH1 | |
| SCHEMBL10800999 | 0.93 | NCEH1 (0.46) | KDM4EALDH1A1GAAHPGDNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900717-A | USEFUL IN THE PREPARATION OF NAPHTHALENEDICARBOXYLIC ACID/2,6-/ | RUTGERSWERKE AG (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4900717-A | USEFUL IN THE PREPARATION OF NAPHTHALENEDICARBOXYLIC ACID/2,6-/ | RUTGERSWERKE AG (DE) | 1990-02-13 | — | — | US | disclosed |